Caffeine is noted to cause bone loss and osteoporosis over time, as shown in a study published in the Journal of Bone and Mineral Research.
In a study published in Behavioral Psychology, coffee has been shown to hinder short-term memory.
Coffee may lead to nutritional deficits because it may block certain nutrients from being absorbed, like iron, which can lead to anemia.
A study conducted by Dr. Jon Gleason at the University of Alabama found that urinary incontinence may be been linked to coffee consumption, because of its diuretic effects and stress on the bladder.
Unfiltered coffee contains kahweol and cafestol which are known to raise cholesterol, according Linus Pauling Institute at Oregon State University.
A Mayo Clinic study recently showed that men who drank more than four cups of coffee (8 oz servings) had a 21% mortality increase.
Though there is a lack of evidence showing that coffee causes cancers, it does contain carcinogens, whether it is caffeinated or not.
Coffee stimulates the adrenals to release adrenaline, which is why coffee gives a burst of energy. However, overindulgence in coffee leads to constant output of adrenaline, placing stress on the adrenals and wearing them out.