This is the easiest beef stew ever because you just toss everything straight into the slow cooker. You can definitely sauté the garlic and onions beforehand, but they’ll flavor the stew regardless. You can also sear the meat before cooking, but it doesn’t hold the juice in, as the common cooking myth would have you believe.
Spread the potatoes out at the bottom of the slow cooker. Then layer in the onions, garlic, carrots, meat, and mushrooms. Pour in the crushed tomatoes and wine. Sprinkle in the oregano, red pepper flakes, and some salt and pepper.
Cook on Low for 6 hours. Serve while hot.