Domilise's Po-Boys

Sandwiches, Bar
5240 Annunciation St (at Bellecastle St.)
New Orleans, LA 70115
(504) 899-9126
10:00am - 6:30pm
10:00am - 6:30pm
10:00am - 6:30pm
10:00am - 6:30pm
10:00am - 6:30pm
10:30am - 7:00pm

The conversation about New Orleans' best po'boys is a serious enough one to have set The Times-Picayune's own restaurant critic Brett Anderson on one of the city's most cherished endeavors: to find the best roast beef po'boy. Sure, that meant hitting up places like Mother's and Parkway, but it was at Domilise's on the unimpressive corner of Annunciation and Bellecastle streets at the end of a trolley ride fairly far west of Bourbon Street where you can find one of New Orleans' best. The quintessential light bread characteristic of the genre topped with supremely thin-sliced roast beef, dressed with a touch of Creole mustard, and covered with gravy will certainly get tongues wagging. Consider Anderson's own words: "I’m prepared to defend these propositions: If a template for a classic New Orleans po’boy joint exists, it’s Domilise’s. "



  • Its impossible to say any shop has the best po boys, but they make a strong claim to that title here. Theyre expensive for po boys, but theyre large and worth every penny. [Eater 38 Member]
  • Favorite po-boy of Better Than Ezra's Tom Drummond.
  • There are countless po'boy joints in the Big Easy, but this one stands apart from the rest. The bread is freshly baked and the shrimp is hot from the fryer - a real "Nawlins" favorite.
  • best poboys in the city, been coming here since I was a kid
  • These are the best po-boys in town. I like the shrimp dressed.
  • The off-the menu special (Anthony Bourdain's favorite) is delicious. Consisting of Roast Beef, Fried Shrimp, Gravy and Swiss Cheese is the closest to perfection you can get out of two pieces of breath
  • "ya sandwich is ready..." :)
  • The fried oyster po boy ($13) is HEAVEN and a small is big enough. Don't skimp on the dressings! (Check out our blog post:
  • If you just want a Poboy, go somewhere else. If you want a great Poboy, come here, but be prepared to wait. It's worth it.
  • Everything
  • Surf and turf
  • fried oyster poboy is delicious but the real winner here are the fried. Theyre like seasoned potato wedges but BETTER.
  • 44 years of visiting. Still made fresh for you greatest
  • Creamy oysters, tasty shrimp and lightly breaded so you can still taste them! Bread is super light, so much so that you wont be too full after. Awesome poboys. Eat a couple ;)
  • The oyster and Shrimp poboys are really tasty
  • Best Po Boy in NOLA
  • They now have good curly fries.
  • the manning's place for po-boys, smaller on the inside - go to this place for po-boys
  • Long lines during lunch but totally worth the wait. I highly recommend the large half & half seafood po boy with fried shrimp and fried oyster. So good!
  • Helluva oyster po boy. Good vibes, wonderful staff

Nearby places

4801 Tchoupitoulas St (at Bordeaux St)
4924 Prytania St
6500 Magazine St