America's 35 Best Pizzas Slideshow

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#20 Regina Pizzeria (Boston)

It may now sport some 20 locations, but the original Regina Pizzeria has been a local hot spot since 1926 when it first opened in the North End of Boston. Their pizzas are made from dough with an 80-year-old family recipe, sauce, whole-milk mozzarella, and natural toppings with no preservatives or additives, and all cooked in a brick oven.

They offer a variety of nearly 20 different pies, some made in a more traditional manner, while others, like the St. Anthony’s pizza with regina sausage, sausage links, roasted peppers, and garlic sauce, are unique.